Viruses are pH sensitive
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Published on March 04th, 2020

The most overlooked aspect of the coronavirus pandemic is the fact that most viruses are pH sensitive. PH medicine offers us a key to treating viral infections that is simple, safe, and inexpensive. The shift in a patient's pH, combined with high doses of vitamin C, is the appropriate basic treatment for home and hospital treatment.

There are many additional treatments like vitamin D, glutathione, iodine, and selenium, even Hydrogen, but the first thing we should resort to is Sodium bicarbonate [Kaiser-Natron ®] that gives us control over the oxygen and Carbon dioxide content offers.

Researchers at Massachusetts General Hospital (MGH) in the US have the "Achilles heel" of most of the viruses that plague humanity uncovered. There are vulnerabilities that can be exploited, but what they look at is not practical or helpful in our fight against viral infections. The so-called “Achilles heel” (or vulnerable point) of most viruses is pH, cell tension and oxygen levels. The pH value is a measure of tension and oxygen saturation. The coronavirus needs a slightly acidic pH value to penetrate the cell.

Simply alkalinizing the blood reduces the cells' susceptibility to the virus. The ability of the influenza virus to release its genome under various acidic conditions has been implicated by medical science in influenza virus transmission. The threshold pH at which fusion is first observed may vary between different serotypes of the membrane protein hemagglutinin (HA) and may correlate with virulence. The acid stability of HA has been linked to the successful transmission of the virus between birds and human hosts.

Coronavirus infectivity is actually extremely sensitive to pH. The coronavirus strain MHV-A59 is quite stable at pH 6,0 (acidic), but is deactivated quickly and irreversibly by a short treatment at pH 8,0 (alkaline). The human coronavirus strain 229E is maximally infectious at pH 6,0. Infection of cells with the coronavirus A59 at pH 6,0 (acidic) instead of pH 7,0 (neutral) leads to a ten-fold increase in the infectivity of the virus.

The data suggest that the coronavirus IBV carries out a direct, low-pH-dependent virus-cell fusion activation reaction. “The fusion of the coronavirus IBV with host cells does not take place at neutral pH, and fusion activation is a pH-dependent process with a half-maximal fusion rate at pH 5,5. Little or no fusion occurred above pH 6,0. "

Raising the pH (to an alkaline state) increases the immune system's ability to kill bacteria, according to the conclusion of the Royal Free Hospital and School of Medicine in London. The viruses and bacteria that cause bronchitis and colds thrive in an acidic environment. Keeping our pH in the slightly alkaline range of 6,8-7,2 can reduce the risk and severity of colds, sore throats and flu attacks.

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With thorough addition of alkalinity, slight attacks of viral infections occur again and again, and the same applies to bacterial and fungal infections. There is a significant decrease in the mean number of colony-forming bacteria and fungi in the lungs of patients with pneumonia, though Sodium bicarbonate [Kaiser-Natron ®] versus saline.

Medical scientists have already concluded that an 8,4% solution of bicarbonate is a safe means of inhibiting the growth of bacteria, fungi and mycobacteria in the airways. Slow infusions of NaHCO3 (bicarbonate) [Kaiser-Natron ®] can also for the treatment of metabolic acidosis without an anion gap and some forms of enlarged anion gap acidosis, a problem that is common enough in ICU patients with severe lung infections.

Viruses infect host cells by fusing with cell membranes at low pH. Hence, they are called "PH-dependent viruses" classified. It has been shown that drugs that increase intracellular pH (alkalinity within the cell) decrease the infectivity of pH-dependent viruses. Since such drugs can cause negative side effects, it makes sense to resort to natural procedures that can achieve the same results. There is no pharmaceutical that comes with that Sodium bicarbonate [Kaiser-Natron ®] can compete to change the pH of body fluids.

The fusion of viral and cellular membranes is pH dependent. "The fusion depends on the acidification of the endosomal compartment.. Fusion at the endosome level is triggered by conformational changes in viral glycoproteins that are induced by the low pH of this cellular compartment. " [1] In membrane biology, fusion is the process in which two originally different lipid bilayers merge their water-repellent nuclei, resulting in a cohesive structure. It has been suggested that that Hepatitis C virus (HCV) infected host cells through a pH-dependent internalization mechanism. This HCVpp-mediated fusion was dependent on low pH, with a threshold of 6,3 and an optimum at around 5,5. [2] When the pH drops to 6 or below, rapid fusion occurs between the viral membranes and the liposomes.

Takeda Pharmaceutical is the newest drug company, alongside Gilead Sciences and AbbVie, to develop a vaccine against the coronavirus. The experimental drug would be made from the blood of coronavirus patients who have recovered from respiratory disease. "While we don't know for sure if it will work, but we think there is definitely a relevant value that could help here, ”said Dr. Rajeev Venkayya, President of Takeda's Vaccines Business. pH medicine will definitely work because viruses are pH dependent and Sodium bicarbonate [Kaiser-Natron ®] is available everywhere and costs next to nothing. Bicarbonate can easily be given intravenously in hospitals.

Inhibition of the replication of the vesicular stomatitis virus (VSV) in LB cells by interferon (IFN) is pH sensitive. Using sensitive intracellular pH (pHi) indicators, the researchers found that IFN treatment significantly increased pHi. The increase in pHi correlated with an increase in the antiviral activity of IFN by primary amines. These results suggested that the IFN-induced increase in pHi may be responsible for the accumulation of G in TGN, thereby causing G-deficient virus particles with reduced infectivity arise. [3]

Sunlight is another important factor
because the action of UV radiation causes the deactivation of viruses.
Viruses survive better in the dark than in sunlight.

The foot and mouth disease virus (FMD virus) capsid is highly acid-labile and tends to break down into pentameric subunits under acidic conditions. to release viral RNA to initiate virus replication.

Understand cell voltage, pH and oxygen levels

Wherever there is a low voltage in the body, the cells begin to have problems which become more serious the lower the voltage (pH) becomes. The lower the voltage, the lower the pH and the lower the oxygen level, which means that the CO2 level also goes down. Chronic illnesses are associated with loss of tension, lower pH levels (acidic conditions), and low O2 and CO2 levels. This means that alkaline tissues have more oxygen in them.

Wherever the body becomes acidic, the tension drops and with it the oxygen content in the tissue. What actually is the pH value? Ultimately, it is a measure of the redox potential. The redox potential is a measure of whether electrons are in excess (and are therefore “electron donors”) or whether electrons are deficient (and are therefore “electron robbers”). Electrons are vital and needed for health and in large quantities for healing and new cell growth.

Dr. David Brownstein wrote: “The human body is constantly in the process of removing old and injured cells and replacing them with healthy new cells. This process can only take place if the voltage of the cells is kept at an optimal level. This process works more effectively when we are young than when we are older. Is in the body (or in a solution) the voltage is a direct reflection of the pH, which is a measure of the degree of acidity or alkalinity of a solution, measured on a scale from 1 to 14. The pH of the human body is a direct reflection of its tension. A low pH (very acidic) indicates a low state of tension. Conversely, a high pH value (strongly alkaline) means a high state of tension. "

The amount of oxygen in cells is determined by voltage. If a cell has enough voltage, it also has enough oxygen. When the cell voltage is low, the amount of oxygen in the tissues is also low. This also applies to the metabolism. When tension and oxygen are low, the metabolism becomes anaerobic, which means there is no oxygen available.

What happened?

  1. 24th January: Treatment Recommendations for New Virus That Crushes Cities
  2. 27th January: Coronavirus Epidemic - Should We Panic Yet? (engl.)
  3. 28th January: Does the coronavirus even kill healthy people? (engl.)
  4. 29th January: The joke of the medical quarantine
  5. 30th January: Navigating Virus Storms and Avoiding Death
  6. 31th January: Dosages and treatments for coronavirus infections
  7. 03. February: Glutathione against the coronavirus
  8. 06. February: They don't want you to know basic virus therapies - water is the most basic treatment
  9. 10. February: World ready to freak out? (engl.)
  10. 13. February: World health experts got it wrong
  11. 17. February: Deadly Viruses and Economical Grim Reapers
  12. 19. February: Meek Coronavirus
  13. 24. February: The world is running out of time
  14. 28. February: Virus, 5G and Pollution Unite to Destroy Wuhan
  15. 02. March: Unreliable coronavirus tests and statistics

References

[1] Viral membrane fusion: is the rhabdovirus glycoprotein G a member of a new class of viral fusion proteins?
Braz J Med Biol Res; vol. 38 no.6; Ribeirão Preto June 2005;
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2005000600002 (engl.)

[2] Hepatitis C virus glycoproteins mediate pH-dependent membrane fusion with liposomes;
Lavillette D et al; J Biol Chem. 2006 Feb 17; 281 (7): 3909-17. Epub 2005 Dec 15;
http://www.ncbi.nlm.nih.gov/pubmed/16356932 (engl.)

[3] Primary amines enhance the antiviral activity of interferon against a membrane virus: role of intracellular pH;
Maheshwari RK (Eng.) et al; J Gen Virol. (English); 1991 Sep; 72 (Pt 9): 2143-52.
http://www.ncbi.nlm.nih.gov/pubmed/1654374 (engl.)

Quelle / Source, Credits to Dr. Mark Sircus:

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